Treatment Outcome of Intranasal Corticosteroid with Oral Antihistamines versus Oral Antihistamines Alone In Allergic Rhinitis
نویسندگان
چکیده
منابع مشابه
Superiority of an intranasal corticosteroid compared with an oral antihistamine in the as-needed treatment of seasonal allergic rhinitis.
BACKGROUND The daily use of either intranasal corticosteroids or histamine(1) (H(1)) receptor antagonists has proved to be efficacious in the treatment of seasonal allergic rhinitis. Most patients, however, use these medications as needed. Our objective was to compare the effectiveness of as-needed use of H(1) receptor antagonists with that of intranasal corticosteroids in the treatment of seas...
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Rhinitis affects millions of people around the world, places a huge burden on the economy and reduces patients' health-related quality of life. Azelastine nasal spray is a second-generation antihistamine, indicated for the treatment of allergic and nonallergic rhinitis in both adults and children. It offers a rapid onset of action (15 min) and flexibility of both dose (i.e., one or two sprays/n...
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BACKGROUND The pathogenesis of vasomotor rhinitis is not understood. It is unlikely that antihistamines, based on their H1 antagonist activity alone, would be effective in this disorder. METHODS Nonetheless, at least one double-blind, placebo-controlled multicenter trial has found that intranasal azelastine relieves symptoms of this disorder better than placebo. The mechanism responsible for ...
متن کاملComparison of antileukotrienes and antihistamines in the treatment of allergic rhinitis.
BACKGROUND The aim of this study was to compare the effect of antileukotriene (anti-LT), antihistamine, and a combination of anti-LT and antihistamine on the symptoms and nasal resistance in allergic rhinitis patients. METHODS We performed a placebo-controlled study, with 120 persistent, moderate to severe allergic rhinitis patients randomly selected to receive the different treatments for 4 ...
متن کاملIntranasal corticosteroids versus oral H1 receptor antagonists in allergic rhinitis: systematic review of randomised controlled trials.
OBJECTIVE To determine whether intranasal corticosteroids are superior to oral H1 receptor antagonists (antihistamines) in the treatment of allergic rhinitis. DESIGN Meta-analysis of randomised controlled trials comparing intranasal corticosteroids with oral antihistamines. SETTING Randomised controlled trials conducted worldwide and published between 1966 and 1997. SUBJECTS 2267 subjects...
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ژورنال
عنوان ژورنال: Annals of International medical and Dental Research
سال: 2017
ISSN: 2395-2814,2395-2822
DOI: 10.21276/aimdr.2017.3.3.en5